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Cancer detection and tissue of origin determination with novel annotation and scoring of cell-free methylated DNA

   
@article{AMJ3978,
	author = {Richard J. Acton and Christopher G. Bell},
	title = {Cancer detection and tissue of origin determination with novel annotation and scoring of cell-free methylated DNA},
	journal = {AME Medical Journal},
	volume = {2},
	number = {8},
	year = {2017},
	keywords = {},
	abstract = {In a recent paper, Guo et al. (1) analysed the methylation of DNA fragments circulating in the blood plasma that are released when cells die. Their analysis used a novel approach to annotate DNA methylation and a methylation status score, which captures both average methylation level and the pattern of co-methylation. They were able to detect lung and colorectal cancers and to predict their tissue of origin.},
	issn = {2520-0518},	url = {https://amj.amegroups.org/article/view/3978}
}