%0 Journal Article
%T Cancer detection and tissue of origin determination with novel annotation and scoring of cell-free methylated DNA
%A Acton, Richard J.
%A Bell, Christopher G.
%J AME Medical Journal
%D 2017
%B 2017
%9 
%! Cancer detection and tissue of origin determination with novel annotation and scoring of cell-free methylated DNA
%K 
%X In a recent paper, Guo et al. (1) analysed the methylation of DNA fragments circulating in the blood plasma that are released when cells die. Their analysis used a novel approach to annotate DNA methylation and a methylation status score, which captures both average methylation level and the pattern of co-methylation. They were able to detect lung and colorectal cancers and to predict their tissue of origin.
%U https://amj.amegroups.org/article/view/3978
%V 2
%P 
%@ 2520-0518