TY - JOUR AU - Huang, Ruyi AU - Lu, Daniel C. PY - 2017 TI - Tune the cord into right chords—activating a “paralyzed” immune system by silencing thoracic interneuron JF - AME Medical Journal; Vol 2 (August 2017): Ame Medical Journal Y2 - 2017 KW - N2 - Spinal cord injury (SCI) results in devastating impairment of motor function. An under-appreciated yet equally important complication in chronic SCI is infection. The increased risk of infection in patients living with SCI has traditionally been attributed to motor-paralysis such as dysphagia or neurogenic bladder resulting in pneumonia or urinary tract infection. However, a condition known as SCI-induced immune depression syndrome is thought to decrease adaptive and innate immunity, leading to increased susceptibility to infections (1). A study by Ueno et al., seeks to elucidate the cellular mechanism of this phenomenon (2). UR - https://amj.amegroups.org/article/view/4015