@article{AMJ4188,
author = {Guri Grimnes and Rolf Jorde},
title = {Vitamin D and bone—the search for the optimal dose},
journal = {AME Medical Journal},
volume = {2},
number = {12},
year = {2017},
keywords = {},
abstract = {Since the discovery that cod liver oil cured rickets back in 1918, bone disease has been the hallmark of vitamin D deficiency. Still, hundreds year later, we do not know the optimal vitamin D intake or levels for our skeleton. As for most nutrients, the effects of vitamin D intake in the body follow a U-shaped pattern—with an increased risk of detrimental effects at both very low and very high intakes, with a broad range of intakes in between regarded safe and sufficient (1). What the thresholds for too little and too much should be for vitamin D, are still not clarified.},
issn = {2520-0518}, url = {https://amj.amegroups.org/article/view/4188}
}