TY  - JOUR
AU  - Grimnes, Guri
AU  - Jorde, Rolf
PY  - 2017
TI  - Vitamin D and bone—the search for the optimal dose
JF  - AME Medical Journal; Vol 2, No 12 (December 2017): Ame Medical Journal
Y2  - 2017
KW  - 
N2  - Since the discovery that cod liver oil cured rickets back in 1918, bone disease has been the hallmark of vitamin D deficiency. Still, hundreds year later, we do not know the optimal vitamin D intake or levels for our skeleton. As for most nutrients, the effects of vitamin D intake in the body follow a U-shaped pattern—with an increased risk of detrimental effects at both very low and very high intakes, with a broad range of intakes in between regarded safe and sufficient (1). What the thresholds for too little and too much should be for vitamin D, are still not clarified.
UR  - https://amj.amegroups.org/article/view/4188