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Immune tolerant HBV and HCC: time to revise our tolerance levels for therapy?

   
@article{AMJ4306,
	author = {Kali Zhou and Norah Terrault},
	title = {Immune tolerant HBV and HCC: time to revise our tolerance levels for therapy?},
	journal = {AME Medical Journal},
	volume = {3},
	number = {2},
	year = {2018},
	keywords = {},
	abstract = {The immune tolerant (IT) phase, the first phase of chronic hepatitis B virus (HBV) infection, has historically been perceived as a benign period in the natural history of this disease. Perinatal infection leads to a prolonged IT phase, with transition to immune clearance with seroconversion to anti-HBe in the second to third decade, whereas immediate progression to immune clearance usually occurs in newly infected children and adults (1).},
	issn = {2520-0518},	url = {https://amj.amegroups.org/article/view/4306}
}