The value of digital rectal examination in clinical practice

The discussed study by Halpern et al. (1) evaluated the value of the digital rectal examination (DRE) in dependence of the prostate specific antigen (PSA) range. In men with a low PSA a suspicious DRE was associated with a higher increase in the relative risk of a clinically significant prostate cancer (CSPC) as compared to those men with higher PSA values.